Genomics LIMS for Next-Generation Sequencing Labs

Managing the complexity from sample to sequence data. Track library preparation, sequencing runs, and demultiplexing workflows with full traceability.

Complete NGS Workflow Management in One System

Built for Genomics Complexity

Core Genomics Entities

Samples and specimen types
DNA/RNA extractions
Library preparations
Library QC measurements
Index assignments
Pooled libraries
Pool quantification
Sequencing runs
Lane assignments
Read structures
Demultiplexed samples
Fastq file tracking
Analysis pipeline runs
Quality control checkpoints
Projects and studies
Customer deliverables
Reagent lot tracking
Index sets and barcodes
Sequencing instruments
Storage locations

Integration Capabilities

Illumina NovaSeq systems
Illumina NextSeq platforms
Illumina MiSeq instruments
Oxford Nanopore MinION
Oxford Nanopore PromethION
qPCR quantification systems
Bioanalyzer integration
TapeStation data import
Fragment Analyzer results
Qubit fluorometer measurements
Plate readers
Thermocyclers
LIMS-to-bioinformatics pipelines
Sample sheet generation
Automated demux CSV import
BaseSpace integration
Custom API connections
Laboratory automation systems
Barcode scanners

Compliance & Traceability

ISO 17025 compliance
ISO 15189 compliance
Complete audit trails
Chain of custody tracking
Sample lineage tracking
Version control
User access controls
Role-based permissions
Electronic signatures
Instrument calibration records
Equipment maintenance logs
Method validation documentation
Standard operating procedures
Quality management integration
Non-conformance tracking
Corrective action records
Regulatory reporting
Data integrity controls
Batch record management
Document management
Training records

Key Features for Next-Generation Sequencing Labs

Purpose-built capabilities that address the unique complexity of genomics workflows, from preventing index clashes to ensuring regulatory compliance.

End-to-End Sample Traceability

Track complete sample lineage from original specimen through library preparation, pooling, and sequencing to final data delivery.

Prevent Costly Index Clashes

Built-in validation detects potential index collisions before pool creation, protecting expensive sequencing runs from failure.

Direct Instrument Integration

Eliminate manual data entry with automated integration to Illumina, Oxford Nanopore, and QC instruments including Bioanalyzer, qPCR, and TapeStation.

Automated Sample Sheet Generation

Generate validated, error-free sample sheets directly from LIMS with correct index sequences, lane assignments, and run parameters.

Centralized QC Management

Consolidate all quality control checkpoints in one system with configurable pass/fail criteria, including library QC, pool quantification, and run metrics.

ISO 17025/15189 Compliance Ready

Built-in audit trails, electronic signatures, and complete documentation meet regulatory requirements without additional overhead.

Genomics Laboratory Management System Built on Odoo

LIMS.SCIENCE runs entirely on Odoo, a powerful ERP system trusted by over 15 million users across the world.

We've adapted it specifically for next-generation sequencing laboratories. You can manage everything from sample tracking and library preparation to sequencing runs, demultiplexing, and compliance in one place.

Configure sequencing protocols, index sets, and QC thresholds for your specific NGS workflows
Track samples through library prep, pooling, sequencing runs, and demultiplexing with complete traceability
Approve or reject results with full audit trails, including QC checks, run validation, and quality flags
Assign user access by role so lab techs, bioinformaticians, QC managers, and clients see only what they need
Centralize multi-site sequencing operations across research facilities, clinical labs, or service providers in one dashboard
Access anywhere via the cloud or install on your own secure server

Need Help?

FAQs

Is this LIMS compliant with ISO 17025 for clinical sequencing labs?

Yes. Our genomics LIMS is built to support ISO 17025 compliance with complete audit trails, electronic signatures, instrument calibration tracking, method validation documentation, and quality management workflows. The system maintains chain of custody records and provides the documentation structure needed for regulatory audits.

Can the system handle multiple sequencing platforms and instruments?

Yes. We support integration with Illumina platforms (NovaSeq, NextSeq, MiSeq), Oxford Nanopore systems, and common QC instruments including Bioanalyzer, TapeStation, qPCR systems, and Qubit. The system can be configured for your specific instrument fleet and workflow requirements.

How does the LIMS prevent index clashes in multiplexed runs?

The system validates index compatibility when creating pooled libraries, checking for potential clashes based on your index sets and sequencing chemistry. You can maintain comprehensive libraries of dual-indexed combinations with automatic validation to protect expensive sequencing runs from index collision failures.

Can we customize workflows for our specific sequencing protocols?

Yes. We support integration with XRF, ICP, AAS, fusion instruments and more. You can also export reports and results to other software or ERP platforms without manual formatting.Absolutely. Built on Odoo’s flexible framework, you can configure library preparation protocols, QC checkpoints, sequencing run parameters, and approval workflows to match your laboratory’s specific processes. We work with you during implementation to adapt the system to your needs.

What sample types and sequencing applications are supported?

The system handles diverse specimen types (tissue, blood, saliva, environmental samples) and sequencing applications including whole genome sequencing (WGS), whole exome sequencing (WES), RNA-seq, targeted panels, metagenomics, and single-cell sequencing. Workflows are customizable for research, clinical, and commercial sequencing operations.

How does demultiplexing data get into the LIMS?

You can import demultiplexing results via CSV upload or integrate directly with your bioinformatics pipeline. The system links demultiplexed samples back to their source libraries and sequencing runs, maintaining complete traceability from sample receipt to final data delivery.

Start Managing Your Sequencing Operations with Purpose-Built Genomics LIMS

Experience how specialized laboratory management software can streamline your NGS workflows from sample tracking through data delivery. See the system in action with a personalized demo tailored to your sequencing operations.

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