Genomics LIMS and NGS Lab Software for Next-Generation Sequencing Workflows
Purpose-built genomics LIMS for NGS labs, managing workflows from sample intake to sequence delivery with sequencing integrations, full traceability and support for ISO/IEC 17025-aligned workflows.
NGS LIMS Configured Around Sample, Library, Run and Analysis States
The sector in practice · Genomics
Two views of your laboratory workflow
Library identity, sequencing yield and read-quality metrics remain connected through technical review, without personal genomic data.
General examples shown for illustrative purposes.
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Genomics LIMS Connecting Logistics, Analytics, QC, Inventory and Statistics
Core Genomics Entities
- Samples and specimen types
- Amplification batches
- DNA/RNA extractions
- Library preparations
- PCR and qPCR assays
- Library QC measurements
- Index assignments
- Plate layouts
- Primer and probe lots
- Ct results
- Pooled libraries
- Pool quantification
- Sequencing runs
- Lane assignments
- Control results
- Read structures
- Demultiplexed samples
- Fastq file tracking
- Analysis pipeline runs
- Quality control checkpoints
- Projects and studies
- Customer deliverables
- Reagent lot tracking
- Index sets and barcodes
- Sequencing instruments
- Storage locations
Integration
- Illumina NovaSeq systems
- Illumina NextSeq platforms
- Illumina MiSeq instruments
- Oxford Nanopore MinION
- Oxford Nanopore PromethION
- qPCR quantification systems
- Real-time PCR instruments
- Nucleic acid extraction systems
- Liquid handlers
- Bioanalyzer integration
- TapeStation data import
- Fragment Analyzer results
- Qubit fluorometer measurements
- Plate readers
- Thermocyclers
- LIMS-to-bioinformatics pipelines
- Sample sheet generation
- Automated demux CSV import
- BaseSpace integration
- Custom API connections
- Laboratory automation systems
- Barcode scanners
Compliance
- Support for ISO/IEC 17025-aligned workflows
- Complete audit trails
- Chain of custody tracking
- Sample lineage tracking
- Version control
- User access controls
- Role-based permissions
- Electronic signatures
- Instrument calibration records
- Equipment maintenance logs
- Method validation documentation
- Standard operating procedures
- Quality management integration
- Nonconformity tracking
- Corrective action records
- Regulatory reporting
- Data integrity controls
- Batch record management
- Reagent lot release records
- Document management
- Training records
- Method verification records
These cover what most sequencing and molecular labs configure. Anything specific to your assays, platforms or accreditation scope gets added during setup.
Genomics LIMS Software Features for Next-Generation Sequencing Labs
Capabilities built for how sequencing and molecular labs actually run, from catching index collisions before a pool is made to holding a result back when a control fails.

Genomics LIMS Solution Built on Odoo
Lims.science runs entirely on Odoo, a powerful ERP system trusted by over 15 million users across the world.
We've adapted it specifically for next-generation sequencing laboratories. You can manage everything from sample tracking and library preparation to sequencing runs, demultiplexing, and compliance in one place.
- Configure sequencing protocols, index sets, and QC thresholds for your specific NGS workflows
- Track samples through library prep, pooling, sequencing runs, and demultiplexing with complete traceability
- Approve or reject results with attributable, time-stamped change histories covering configured QC checks, run review and quality flags
- Assign user access by role so lab techs, bioinformaticians, QC managers, and clients see only what they need
- Centralise multi-site operations across research facilities, molecular testing labs, or sequencing service providers in one dashboard
- Access anywhere via the cloud or install on your own secure server
Need Help?
FAQs
What is a LIMS in genomics?
A genomics LIMS tracks the path a sample takes through a sequencing lab. Receipt and accessioning, DNA or RNA extraction, library preparation, index assignment, pooling, the run itself, then demultiplexing and delivery of FASTQ files. It holds the QC measurement taken at each handoff and keeps the audit trail accreditation bodies ask to see. Labs without one usually run this across spreadsheets and sample sheets that drift out of step with what the instrument actually did.
How does this LIMS support ISO/IEC 17025 for sequencing laboratories?
The genomics LIMS can be configured to support requirements relevant to the laboratory’s ISO/IEC 17025 scope. Attributable, time-stamped change histories, electronic approval or signature controls, instrument records, method-validation documentation and controlled records are specified and validated for the intended use.
Can the system handle multiple sequencing platforms and instruments?
Yes. We support integration with Illumina platforms (NovaSeq, NextSeq, MiSeq), Oxford Nanopore systems, and common QC instruments including Bioanalyzer, TapeStation, qPCR systems, and Qubit. The system can be configured for your specific instrument fleet and workflow requirements.
How does the LIMS prevent index clashes in multiplexed runs?
The system validates index compatibility when creating pooled libraries, checking for potential clashes based on your index sets and sequencing chemistry. You can maintain comprehensive libraries of dual-indexed combinations with automatic validation to protect expensive sequencing runs from index collision failures.
Can we customise workflows for our specific sequencing protocols?
Yes. Library-preparation protocols, QC checkpoints, sequencing-run parameters, roles and approval gates are configured around the laboratory’s authorised process. Changes can be version-controlled and effective-dated during implementation and ongoing change control.
What sample types and sequencing applications are supported?
Whole genome, exome, targeted panels, amplicon, RNA-seq and metagenomics, with sample types from blood and tissue through to swabs, soil and food matrices. Molecular work that stops short of sequencing is handled the same way. qPCR and endpoint PCR run as their own workflows, with 96 and 384 well plate layouts, Ct capture per well, and extraction batches tracked back to the kit lot used. Assay definitions covering targets, cycling parameters and acceptance criteria are configured once and applied to every run after that.
Is there a free genomics LIMS, and what does yours cost?
Free and open source options exist, and for a small lab tracking a handful of samples they can be enough. Where they usually run out is sequencer integration, index clash validation, reagent lot traceability, and the audit records an assessor expects to see. Labs tend to start looking again at the point accreditation becomes real.
We price well below the enterprise platforms most genomics labs get quoted, and cost scales with your team and lab size rather than with test volume. See the pricing page for current figures.
How does demultiplexing data get into the LIMS?
You can import demultiplexing results via CSV upload or integrate directly with your bioinformatics pipeline. The system links demultiplexed samples back to their source libraries and sequencing runs, maintaining complete traceability from sample receipt to final data delivery.
Start Managing Your Sequencing and Molecular Workflows in One System
Review a LIMS configured for your NGS workflow, from accessioning and extraction through library preparation, pooling, sequencing, QC review and data delivery.