Genomics LIMS and NGS Lab Software for Next-Generation Sequencing Workflows

Purpose-built genomics LIMS for NGS labs, managing workflows from sample intake to sequence delivery with sequencing integrations, full traceability, and ISO/IEC 17025 compliance.

Complete NGS LIMS for Next-Generation Sequencing Workflow Management

Sequencing run interface showing NovaSeq 6000 run parameters and lane-level QC metrics
Track run parameters, instrument details, and lane-level performance metrics.
Demultiplexing results showing sample yields, Q30 scores, and pass/fail status across runs
Monitor demultiplexing results with sample-level yield and quality metrics.
Index set interface displaying IDT90 with 96 dual-indexed sequences and their properties
Manage index libraries and prevent clashes with complete sequence tracking.
Sample tracking list showing specimen type, concentration, and status in a genomics LIMS
Track every sample from intake through sequencing, with full status visibility across projects.
Library preparation records showing protocol, index set, molarity, and QC pass status
Log library prep details, assign index sets, and confirm QC pass before pooling.

Genomics LIMS Built for Sequencer Integration and Workflow Complexity

Core Genomics Entities

Samples and specimen types
Amplification batches
DNA/RNA extractions
Library preparations
PCR and qPCR assays
Library QC measurements
Index assignments
Plate layouts
Primer and probe lots
Ct results
Pooled libraries
Pool quantification
Sequencing runs
Lane assignments
Control results
Read structures
Demultiplexed samples
Fastq file tracking
Analysis pipeline runs
Quality control checkpoints
Projects and studies
Customer deliverables
Reagent lot tracking
Index sets and barcodes
Sequencing instruments
Storage locations

Integration

Illumina NovaSeq systems
Illumina NextSeq platforms
Illumina MiSeq instruments
Oxford Nanopore MinION
Oxford Nanopore PromethION
qPCR quantification systems
Real-time PCR instruments
Nucleic acid extraction systems
Liquid handlers
Bioanalyzer integration
TapeStation data import
Fragment Analyzer results
Qubit fluorometer measurements
Plate readers
Thermocyclers
LIMS-to-bioinformatics pipelines
Sample sheet generation
Automated demux CSV import
BaseSpace integration
Custom API connections
Laboratory automation systems
Barcode scanners

Compliance

ISO/IEC 17025 compliance
Complete audit trails
Chain of custody tracking
Sample lineage tracking
Version control
User access controls
Role-based permissions
Electronic signatures
Instrument calibration records
Equipment maintenance logs
Method validation documentation
Standard operating procedures
Quality management integration
Non-conformance tracking
Corrective action records
Regulatory reporting
Data integrity controls
Batch record management
Reagent lot release records
Document management
Training records
Method verification records

These cover what most sequencing and molecular labs configure. Anything specific to your assays, platforms or accreditation scope gets added during setup.

Odoo

Genomics LIMS Solution Built on Odoo

Lims.science runs entirely on Odoo, a powerful ERP system trusted by over 15 million users across the world.

We've adapted it specifically for next-generation sequencing laboratories. You can manage everything from sample tracking and library preparation to sequencing runs, demultiplexing, and compliance in one place.

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FAQs

A genomics LIMS tracks the path a sample takes through a sequencing lab. Receipt and accessioning, DNA or RNA extraction, library preparation, index assignment, pooling, the run itself, then demultiplexing and delivery of FASTQ files. It holds the QC measurement taken at each handoff and keeps the audit trail accreditation bodies ask to see. Labs without one usually run this across spreadsheets and sample sheets that drift out of step with what the instrument actually did.

Yes. Our genomics LIMS is built to support ISO/IEC 17025 compliance with complete audit trails, electronic signatures, instrument calibration tracking, method validation documentation, and quality management workflows. The system maintains chain of custody records and provides the documentation structure needed for regulatory audits.

Yes. We support integration with Illumina platforms (NovaSeq, NextSeq, MiSeq), Oxford Nanopore systems, and common QC instruments including Bioanalyzer, TapeStation, qPCR systems, and Qubit. The system can be configured for your specific instrument fleet and workflow requirements.

The system validates index compatibility when creating pooled libraries, checking for potential clashes based on your index sets and sequencing chemistry. You can maintain comprehensive libraries of dual-indexed combinations with automatic validation to protect expensive sequencing runs from index collision failures.

Yes. We support integration with XRF, ICP, AAS, fusion instruments and more. You can also export reports and results to other software or ERP platforms without manual formatting.Absolutely. Built on Odoo’s flexible framework, you can configure library preparation protocols, QC checkpoints, sequencing run parameters, and approval workflows to match your laboratory’s specific processes. We work with you during implementation to adapt the system to your needs.

Whole genome, exome, targeted panels, amplicon, RNA-seq and metagenomics, with sample types from blood and tissue through to swabs, soil and food matrices. Molecular work that stops short of sequencing is handled the same way. qPCR and endpoint PCR run as their own workflows, with 96 and 384 well plate layouts, Ct capture per well, and extraction batches tracked back to the kit lot used. Assay definitions covering targets, cycling parameters and acceptance criteria are configured once and applied to every run after that.

Free and open source options exist, and for a small lab tracking a handful of samples they can be enough. Where they usually run out is sequencer integration, index clash validation, reagent lot traceability, and the audit records an assessor expects to see. Labs tend to start looking again at the point accreditation becomes real.

We price well below the enterprise platforms most genomics labs get quoted, and cost scales with your team and lab size rather than with test volume. See the pricing page for current figures.

You can import demultiplexing results via CSV upload or integrate directly with your bioinformatics pipeline. The system links demultiplexed samples back to their source libraries and sequencing runs, maintaining complete traceability from sample receipt to final data delivery.

Start Managing Your Sequencing and Molecular Workflows in One System

Experience how specialized laboratory management software can streamline your NGS workflows from sample tracking through data delivery. See the system in action with a personalized demo tailored to your sequencing operations.

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